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LB2

Cancer types

30 TCGA cancer types were analysed and 29 have candidates. Select a cancer type to explore its genes, or sort the columns to compare them.

Candidates with plasma Cell-free RNA (cfRNA)RNA fragments that circulate in blood plasma outside cells. Most come from blood cells; a small share comes from other tissues, including tumors. evidenceProtein-coding, not detectedNon-coding, cannot be checkedBar length is the number of candidates (48,527 in total).
Thoracic
LUSCLung squamous cell carcinoma4983382,15648%> 0.9990 OS
MESOMesothelioma872881,37845%0.99640 OS
LUADLung adenocarcinoma5133471,36446%0.99917 PFI
THYMThymoma1192Only 2 normal samples; at least 10 are needed–––
Gastrointestinal
CHOLCholangiocarcinoma361194,91543%0.9990 PFI
STADStomach adenocarcinoma4142102,58434%0.9960 OS
ESCAEsophageal carcinoma1816662,24641%> 0.9990 PFI
LIHCLiver hepatocellular carcinoma3691601,62643%0.99860 PFI
COADColon adenocarcinoma2883491,35643%1.0000 PFI
READRectum adenocarcinoma923181,35541%1.0000 PFI
PAADPancreatic adenocarcinoma1781711,13660%0.99474 PFI
Genitourinary
KIRCKidney renal clear cell carcinoma5301001,26739%0.99159 OS
TGCTTesticular germ cell tumors1481651,16538%1.0000 PFI
BLCABladder urothelial carcinoma4072868042%0.9982 OS
PRADProstate adenocarcinoma49515264936%0.99152 PFI
KIRPKidney renal papillary cell carcinoma2886055342%0.99447 PFI
KICHKidney chromophobe665334345%0.9978 PFI
Gynecologic
OVOvarian serous cystadenocarcinoma419883,08441%0.9980 PFI
CESCCervical squamous cell carcinoma and endocervical adenocarcinoma304812,57443%1.0000 OS
UCSUterine carcinosarcoma57782,18348%1.0000 PFI
UCECUterine corpus endometrial carcinoma18010183060%> 0.9990 PFI
Breast
BRCABreast invasive carcinoma1,09229259063%0.9990 OS
Endocrine
PCPGPheochromocytoma and paraganglioma1771313,55345%0.9989 PFI
THCAThyroid carcinoma50433868564%0.9950 PFI
ACCAdrenocortical carcinoma7712854832%1.00081 PFI
Central nervous system
LGGBrain lower grade glioma5091,1523,08438%0.99862 PFI
GBMGlioblastoma multiforme1531,1571,81637%1.0000 OS
Head and neck
HNSCHead and neck squamous cell carcinoma518991,46351%0.9982 OS
Skin
SKCMSkin cutaneous melanoma1025571,36358%1.0000 PFI
Soft tissue
SARCSarcoma2583981,98141%> 0.9990 PFI

Shared across TCGA projects

Some clinical terms span two TCGA projects. These views list the genes that are candidates in both, from the separate analyses above; nothing is pooled.

Not analysed

Without normal tissue from the same organ, LB2 cannot tell cancer-specific genes from genes that simply mark the organ, so these cancer types were left out:

  • DLBCLymphoid neoplasm diffuse large B-cell lymphoma (47 tumors; no normal lymph node tissue)
  • UVMUveal melanoma (79 tumors; no normal eye tissue)

Acute myeloid leukemia is not in this set: its TCGA samples are blood-derived rather than solid primary tumors.