DIO2

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LB2

LB2 nominates cell-free RNA candidates from public tissue and blood data. It is a screen for research: every candidate still needs measurement in patient plasma before it means anything clinically.

Not for diagnosis or treatment decisions.

Data sources

TCGA and GTEx RNA-seq (UCSC Xena Toil recompute)
TCGA Pan-Cancer Clinical Data Resource
Human Protein Atlas, immune cells
exoRBase
GEO GSE174302 plasma cfRNA
GENCODE v23 gene annotation

Project

Methods and limitations
Download the data
How to cite
Source code (GitHub)

Code released under the MIT License. If you use these results, cite LB2 and the datasets it is built on.